
What is atherosclerosis?
Atherosclerosis is plaque building up inside the walls of your arteries. Plaque contains cholesterol, fat, blood cells and calcium.
It starts in childhood and progresses slowly for decades, narrowing the arteries until it can cause hospitalization, disability and death.
The same process can affect arteries throughout the body: the heart (angina, heart attack), the brain (TIA, stroke), and the legs, kidneys and gut.
How does plaque lead to a heart attack or stroke?
Plaque is not simply fat in a pipe. It is a slow inflammatory response inside the artery wall, started by damage from high blood pressure, smoking, unhealthy cholesterol or other stressors.
LDL cholesterol collects where the wall is injured and white blood cells move in. Over the years the wall thickens and the channel narrows.
The dangerous turn comes when plaque ruptures. A blood clot can then block blood flow abruptly, turning a long, quiet process into a heart attack, stroke or limb emergency.
Which risks can you change?
Four high-impact risks can be changed: high blood pressure, unhealthy cholesterol, tobacco (smoking and vaping) and diabetes.
Age, male sex, genes and family history cannot be changed. More risk factors usually mean a greater risk of complications.
What are the warning signs?
Mild atherosclerosis usually causes no symptoms. Earlier clues can include chest pressure with exertion, leg pain when walking and slow-healing foot wounds.
Call 911 for signs of a heart attack: chest pressure or pain, shortness of breath, a cold sweat, weakness or faintness, or pain in the jaw, neck, back, arms or shoulders.
Call 911 for signs of a stroke: sudden weakness of the face, arm or leg, trouble speaking or seeing, loss of balance, or a severe unexplained headache.
For either one, do not drive yourself: emergency treatment is time-sensitive.
How can you lower your risk?
Know your numbers before symptoms. A yearly wellness visit checks blood pressure, cholesterol, blood sugar and weight, and estimates your risk. Symptoms or a higher risk may lead to further tests.
Daily habits matter: eat mostly whole foods, move regularly, avoid tobacco and aim for 7–9 hours of sleep. When needed, medicines can lower cholesterol, control blood pressure or prevent clots.
A question to bring to your next visit: “What is my cardiovascular risk, and which one change matters most now?”
Educational overview, not personal medical advice.
References
- National Heart, Lung, and Blood Institute (NIH). What Is Atherosclerosis. View source
- National Heart, Lung, and Blood Institute (NIH). Atherosclerosis: Causes and Risk Factors. View source
- MedlinePlus (National Library of Medicine). Atherosclerosis. View source
- Centers for Disease Control and Prevention. Heart Disease Risk Factors; Heart Attack Symptoms; Stroke Signs and Symptoms.
- National Heart, Lung, and Blood Institute (NIH). Atherosclerosis: Diagnosis. View source
- National Heart, Lung, and Blood Institute (NIH). Atherosclerosis: Prevention. View source
- American Heart Association. Life’s Essential 8.
- Harvard T.H. Chan School of Public Health. Healthy Eating Plate. View source
Book an appointment
Choose a time online with Dr. Vijay Katari, MD at our Frisco or McKinney office, or call (214) 884-2774.